どうもない => No problem N3
Confirm
てもどうなるものでもない => It's no use; can't do anything N3
Invariant
どうも => Confused, bewildered N3
Emphasize
どうも => Not sure... N3
Vague
どうも => Used to greet N5
How to say the beginning
~はどう(で)あれ      => however; whatever​ ~. N1
どうりで => indeed,it's no wonder N2
Base, base
どうも ... そうだ/ ようだ/ らしい => It seems, probably N3
Speculation
はどうですか => how about; how is N5
はどうですか => how about; how is N5
Doubt
~どうにもならない/ できない => not … by any means; no matter how hard one tries, cannot ~ N1
Ability
…どうりがない => No reason... N2
Emphasize negative meaning