... 前に => Before ... N4
Relationship before and after
... 前に => ... in front of, before N4
Relationship before and after
前に => before; in front of ~ N5
を前提に => On the premise of N1
Premise
手前 => considering; before; in front of; one’s standpoint N1
に先駆けて => prior to; to be the first (pioneer); being ahead of ~ N1
[可能系「かのうけい」] => Can, be able to, be possible to N4
Can, Should, Must
~[前「まえ」]に => Before N/Vる(occurs/happens) N5
Time
当然だ/当たり前だ => natural; as a matter of course N2
に[先駆「さきが」]けて => The earliest, very first in A; Ahead of A, in advance of A N1
Time, Situation