は~で有名 => famous for ~ N3
... はずみ.... => So N2
Result
を問わず => regardless of; irrespective of; no matter~ N2
必ずしも~とは限らない => Not necessarily; not always N3
~によらず      => regardless of ~ N1
…ば…はずだ => If ... then perhaps ... N3
Speculation
まずは => Temporary, first of all N5
Consider it
~やむをえず  => unavoidable, no other way to do something N2
Necessity, obligation
はずだ/はずがない => it must be; it should be (expectation)/cannot be (impossible) N3
…はずではなかった => cannot be (impossible) N3
Surprised
をはじめ/をはじめとする => For example, A N2
Lists, Examples
を[問「と」]わず => Disregarding A; Without relation to A N2
Considering, Concerning