[中心「ちゅうしん」]に => With A as the center N2
Miscellaneous
[最中「さいちゅう」] => In the middle of A N3
Time, Situation
中 => Throughout, all over, during the course of N5
Time
そうにない => N2
Potential, Possibility
にほかならない => Only A N2
Reason, Result, Response
ずにはおかない/ないではおかない => Will definitely A, N1
Will, Decision, Doing
めったにない => Rarely N3
Degree. Level, Amount
ずにはすまない/ないではすまない => A must be done N1
Potential, Possibility
に[相違「そうい」]ない => No doubt N2
Information, Report
ずにはいられない/ないではいられない => Can't help but A; A is unavoidable N2
Will, Decision, “Doing”
に[違「ちが」]いない => Without a doubt, A N2
Information, Report
わけにはいかない => Must not A, Must A N3
Needs, Requirement