[極「きわ」]み/[極「きわ」]まりない => Extremely A N1
Degree/ Level/Amount
~きわまる/きわまりない(~極まる/極まりない)      => extremely; very ~ N1
... 反対に => on the contrary N3
Compare
に対して => towards; against; regarding; in contrast with ~​ N3
のに対して => towards; against; regarding; in contrast with ~ N2
[極「きわ」]まる => Extremely A, could not be more A N1
Adjectival, Descriptions
…と (は) はんたい (反対)に => opposition; resistance; antagonism; objection; dissent N3
Compare
に[対「たい」]して/に[対「たい」]しては => In response to (topic) A, in regards to A, considering A, in contrast to A N3
Reason, Result, Response
に[対「たい」]して/に[対「たい」]しては => In response to (topic) A, in regards to A, considering A, in contrast to A N2
Reason, Result, Response