を頼りに => to rely on / with the aid of something N2
に行く/に来る/に帰る => go/arrive/go back (to do something) N5
を[頼「たよ」]りに => With the help of A; thanks to A N2
Based, Focused, Depending on
以来 => since; henceforth ~ N2
ように言う/頼む/注意する/伝える => to convey; to report; to transmit; to communicate; to tell; to impart; to propagate; to teach. N3
にたる,にたりる => Enough to/for A, Sufficient for A, Worthy of A N1
Need/Requirements
出す => to begin to; to start to; to burst into; ... out (e.g. to jump out, to carry out)​ N4
にする => にする N4
て[以来「いらい」] => After A, B (continuous action/condition N2
Information, Report
…にはむりがある => difficult to do; is unreasonable / unrealistic / impossible N3
Vague
へ => Go to N, head to N , Often followed by verbs like 行く/いく, 来る/くる, 向かう/むかう… N5
Particles
~をかわきりに(~を皮切りに)      => One after another; starting with ~ N1