てしょうがない/てしかたがない => Very A; Really A; Extremely A N2
Degree, Level, Amount
~としたことが => ~ surprised N1
Surprised
に先立って => before; prior to ~ N2
に[先立「さきだ」]って/に[先立「さきだ」]ち/に[先立「さきだ」]つ => Before A occurs/takes place N2
Time, Situation
しかしながら => however, nevertheless N2
Things do not match the prediction
て仕方がない/てしょうがない => can't help but; very; extremely ~ N2
よりしかたがない => There is no choice but, Can't be helped, Inevitable N2
Limit
たいがい => in general N2
Repetition, habit
たいして…ない => ~is not much of~ N3
Emphasis on degree
~たいしたことはない => trivial,not amounting to much N1
Emphasize the negative meaning
たしかに/なるほど~かもしれない => might; perhaps N3
Speculation
ためしがない => is never the case; has never happened; I have never seen or heard of ~ N1
Criticize